Bifidobacterium animalis subsp. lactis – BS01 (LMG P-21384)

    Gastroenterology strain | Constipation – Leaky gut

    Characteristics

    DAILY DOSAGE IN CLINICAL STUDY
    1) 5 billion CFU
    2) 10 billion CFU
    3) 5 billion CFU
    4) 5 billion CFU uncoated and 1 billion cells microencapsulated

    FUNCTIONALITY
    Constipation • Intestinal transit • Reduction of gastrointestinal discomfort • Leaky gut

    Scientific support

    Human clinical trials
    1) Del Piano M. et al. The use of probiotics in healthy volunteers with evacuation disorders and hard stools. A double blind, randomized, placebo-controlled study. J Clin Gastroenterol, 2010; 44(8):S30-34.
    2) Del Piano M. et al. The use of probiotics in the treatment of constipation in the elderly. CIBUS, 2005; 1(1):23-30.
    3) Dimidi E. et al. The effect of probiotics on functional constipation in adults: a systematic review and metanalysis of randomized controlled trials. Am J Clin Nutr 2014;100:1075–84.
    4) Del Piano M. et al. Comparison of the Kinetics of Intestinal Colonization by Associating 5 Probiotic Bacteria Assumed Either in Microencapsulated or in a Traditional, Uncoated Form. J Clin Gastroenterol 2012;46:S85-S92.


     

    Immunology strain | Immune stimulation

    Characteristics

    FUNCTIONALITY
    Strengthening of natural defences and natural immunity

    Scientific support

    In vitro study
    Mogna L. et al. Micronized Cells of the Probiotic Strain Bifidobacterium lactis BS01 Activate Monocyte Polarization: A New Approach. J Clin Gastroenterol. 2018;52:S57-S61.


    Immunology blend | Immune stimulation

    • Lactobacillus rhamnosus – LR04 (DSM 16605)
    • Lactobacillus rhamnosus – LR05 (DSM 19739)
    • Lactobacillus plantarum – LP01 (LMG P-21021)
    • Lactobacillus plantarum – LP02 (LMG P-21020)
    • Bifidobacterium animalis subsp. lactis – BS01 (LMG P-21384)

    Characteristics

    DAILY DOSAGE IN CLINICAL STUDY
    2.5 billion CFU + 2.5 billion CFU + 2.5 billion CFU + 2.5 billion CFU + 5 billion CFU + FOS or GOS

    FUNCTIONALITY
    Reinforcement of the natural defences • Reduction of the intestinal discomfort • Rebalance of the intestinal microbiota

    Scientific support

    Human clinical trial
    1) Pregliasco F. et al. A New Chance of Preventing Winter Diseases by the Administration of Symbiotic Formulations. Journal of Clinical Gastroenterology, 2008; 42(2): 224-233.
    2) Belcaro G. et al. Prevention of flu episodes with colostrum and Bifivir compared with vaccination: an epidemiological, registry study. Panminerva Medica 2010;52:269-75.

    In vitro study
    Mogna L. et al. Micronized Cells of the Probiotic Strain Bifidobacterium lactis BS01 Activate Monocyte Polarization: A New Approach. J Clin Gastroenterol. 2018;52:S57-S61.


    Immunology blend | Immune stimulation

    • Bifidobacterium animalis subsp. lactis – BS01 (LMG P-21384)
    • Lactobacillus rhamnosus – LR04 (DSM 16605)
    • Lactobacillus plantarum – LP02 (LMG P-21020)

    Characteristics

    DAILY DOSAGE IN CLINICAL STUDY
    10 billion CFU + 10 billion CFU + 10 billion CFU + 3g

    FUNCTIONALITY
    Reinforcement of the natural defences • Reduction of the incidence, severity and duration of Acute Respiratory Infections (ARI) during the cold season

    Scientific support

    Human clinical trial
    Pregliasco F. et al. A New Chance of Preventing Winter Diseases by the Administration of Symbiotic Formulations. Journal of Clinical Gastroenterology, 2008; 42(2): 224-233.

    In vitro study
    Mogna L. et al. Micronized Cells of the Probiotic Strain Bifidobacterium lactis BS01 Activate Monocyte Polarization: A New Approach. J Clin Ga- stroenterol. 2018;52:S57-S61.


    Dermatology blend | Atopic dermatitis

    • Bifidobacterium animalis subsp. lactis – BS01 (LMG P-21384)
    • Lactobacillus rhamnosus – LR05 (DSM 19739)

    Characteristics

    DAILY DOSAGE IN CLINICAL STUDY
    1 billion

    FUNCTIONALITY
    Atopic dermatitis

    Scientific support

    Human clinical trial
    Manzotti G. et al. Probiotics as a Novel Adjuvant Approach to Atopic Dermatitis. Journal of Contemporary Immunology (2014) Vol. 1 No. 2 pp. 57-66.


    Anti-aging strain | Antioxidant

    Characteristics

    FUNCTIONALITY
    Antioxidant activity • Reduced glutathione (GSH) and superoxide dismutase (SOD) production

    Scientific support

    Internal in vitro data available upon request on above-mentioned functions and strains


    Gut-brain blend | Mood and sleep quality

    • Lactobacillus rhamnosus – GG (ATCC 53103)
    • Bifidobacterium animalis subsp. lactis – BS01 (LMG P-21384)
    • Bifidobacterium breve – BR03 (DSM 16604)
    • Bifidobacterium longum – BL03 (DSM 16603)

    Characteristics

    DAILY DOSAGE IN CLINICAL STUDY
    GG 25 billion CFU + BS01 15 billion CFU + BR03 5 billion CFU + BL03 5 billion CFU

    FUNCTIONALITY
    Sleep improvement and cognitive symptoms improvement in patients with encephalomyelitis/chronic fatigue syndrome

    Scientific support

    Human clinical trial
    Wallis A. et al. Open-label pilot for treatment targeting gut dysbiosis in myalgic encephalomyelitis / chronic fatigue syndrome: neuropsychological symptoms and sex comparisons. J Transl Med 2018, 16:24.